Kent Peterson
Fluid Imaging Technologies, USA
Title: Use of Novel Flow Imaging Particle Analysis in Biopharmaceutical Formulation (FlowCam®)
Biography
Biography: Kent Peterson
Abstract
Flow Imaging particle analysis has shown great promise for analysis of sub-visible particulates in parenterals, especially for protein aggregates. The ability to detect transparent particles, along with the ability to differentiate them based upon shape parameters, yields significantly more detailed and accurate information than can be acquired using common laser diffraction and light obscuration techniques. The addition of color information, along with sophisticated statistical pattern recognition algorithms, can also enable these systems to differentiate and quantify silicon oil droplets and air bubbles found in parenterals. This presentation will present the techniques used to accomplish this.