Tudor Arvinte
University of Geneva, Switzerland
Title: New analytical methods to measure protein aggregates in biopharmaceuticals
Biography
Biography: Tudor Arvinte
Abstract
A good characterisation of the protein aggregation states and of the presence of particulate matter in biopharmaceuticals can only be achieved through a convergence of evidence from numerous classical and orthogonal analytical methods. Based on case studies, different new orthogonal methods will be presented. No single method can be used as an absolute characterisation of the aggregation states. Only by using together many different, complementary methods we can obtain reliable conclusions and reveal an abroad picture on the protein aggregation states and the presence of particulate matter in biopharmaceuticals.
