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Eduard Rogatsky

Eduard Rogatsky

Yeshiva University, USA

Title: LC/MS method transfer surprises and troubleshooting

Biography

Biography: Eduard Rogatsky

Abstract

Different chromatographic and mass spectrometry instrumentations are used in modern bioanalytical laboratories. We noticed that transfer of existent liquid chromatography-mass spectrometry method from one LC/MS system to another is not a simple task. In addition, even adoption of an already published and well validated method is not as straightforward as one would expect. On real world examples, we will discuss instrument-dependent, sample-dependent, and method-dependent variability and implications. To solve these issues, it requires detailed understanding of the method, hardware, assay parameters and analyte nature.

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